Virgin Galactic
http://www.virgingalactic.com/
Virgin Galactic is the world's first spaceline and the anchor tenant of Spaceport America. Virgin Galactic plans to create a five-star destination experience to accommodate customers, their families, and space enthusiasts at Spaceport America, where they will operate their Spaceship II and White Knight II spacecraft.

UP Aerospace
http://www.upaerospace.us.com
UP Aerospace, Inc. was the first company to launch a commercial payload at New Mexico’s Spaceport America. Currently based out of Colorado, they offer complete payload recovery and a wide range of tracking, telemetry, and avionics options.

White Sands Missile Range (WSMR)
http://www.wsmr.army.mil/
Spaceport America is in close proximity to White Sands Missile Range, which is advantageous for business. First, White Sands is the only place in the United States, other than the White House, with restricted airspace to infinity. Second, as the world’s premier missile test range, White Sands is prepared to meet the research, development, and testing needs of the private sector. The facility encompasses 3,200 square miles and is the largest open-air/over-land missile range in the Western hemisphere.

The X PRIZE Foundation
http://www.xprize.org/
The X PRIZE Cup is an annual air and space expo designed to bring together all sections of the aerospace industry to demonstrate their capabilities for the general public. The event features live rockets, static displays, competitions and presentations by some of the industry’s leading minds.

Rocket Racing League®
http://www.rocketracingleague.com/
The Rocket Racing League is an aerospace sports and entertainment organization that combines the competition of racing with the excitement of rocketry. RRL will organize, host and run rocket racing competitions across the United States, with semi-finals in Reno, Nevada, and finals taking place each year at the X Prize Cup in New Mexico, once Spaceport America is complete.

Lockheed Martin
http://www.lockheedmartin.com/ 
As one of the nation’s top aerospace companies, Lockheed Martin of Bethesda, Maryland, has been testing new launch and recovery technologies at Spaceport America. Lockheed Martin employs about 140,000 people worldwide and reported 2006 sales of $39.6 billion.

Payload Specialties
http://www.payloadspecialties.net/
Presently based in Kingsville, Missouri, Payload Specialties launches sounding rockets and heavy lift vehicles for companies involved with the research and development of commercial space technologies and educational payloads. Once a year, or as opportunity permits, the company offers payload space to students on a sounding rocket mission on an application basis to the mid school, high school and university levels

Microgravity Enterprises, Inc (MEI)
http://www.microgravityenterprises.com/
Microgravity Enterprises, Inc., located in Albuquerque, NM, is focused on affordable rocket flight for commercial and educational purposes. Microgravity Enterprises, Inc., has conducted several flights from Spaceport America already, flying special commercial ingredients into space for use in consumer products available at a wide variety of retail stores.